Discover a refreshed, youthful look with a 2-in-1 facial injectable that provides an instant lift

HArmonyCa® combines CaHA with HA in one dual-action injectable, delivered  

as a single treatment into the deep dermal, sub-dermal, or supra-periosteal layers in the cheek and malar areas of the midface, as well as the lateral face and jawline.

HArmonyCa® is powered by DART™ – Dual Action Rejuvenating Technology.

 HA particles diffuse between collagen fibres of the lower dermal layer for an immediate lifting effect.

CaHA microspheres work deep within the dermis to form a scaffold that supports fibroblast function.

As HArmonyCa®’s HA-based carrier gel degrades over time, CaHA supports the body’s own collagen production to build a firm and dense framework in its place, for a long-lasting lift.

Before delivering any treatment, we assess our patients’ medical history,  

their treatment goals, and the regions to be treated, to create a bespoke treatment plan that ensures desired outcomes. 

HArmonyCa® contains lidocaine, an anesthetic, to reduce pain our patients may  

experience during treatment.

HArmonyCa® should be injected into the deep dermal, sub-dermal, or supra-periosteal layers in the midface (cheek and malar area), lateral face, and jawline.

It should not be injected into the glabellar or periocular areas or into the lips  

or perioral region.

Two possible injection techniques include:

• The C approach: treat patients using the C approach, which includes the zygomatic arch, jaw ramus, and jawline. Utilize the three entry points located in the jowl, jaw angle, and jaw ramus to achieve full coverage of the treatment areas.

• The C+ approach: treat patients using the C+ approach, which includes the zygomatic arch, jaw ramus, jawline, pre-jowl sulcus, and the submalar area. Utilize the three entry points located in the jowl, jaw angle, and jaw ramus to achieve full coverage of the  

treatment areas.

Most single-agent collagen stimulators are unable to provide an instant lift that holds as well as sustained collagen stimulation.

HArmonyCa® allows you to target multiple signs of aging by lifting, firming,  

and tightening the skin.

Patients should be advised that they should wait 24 hours before participating in any strenuous activity after treatment with HArmonyCa®. They should also avoid tanning lamps or exposing themselves to sunlight or extreme weather conditions during that time.  

They may resume wearing makeup 12 hours after the procedure.

It is possible to use HArmonyCa® alongside the JUVÉDERM® range that a treatment plan for optimal results is based on the individual and an assessment done in clinic .

For larger volume losses related to bone structure and/or deep fat pads, or if the patient shows a lack of skin firmness and/or loss of collagen, patients should be treated with JUVÉDERM® first (midface/lower face) and then HArmonyCa®.

Note that the safety and efficacy of HArmonyCa® has not been evaluated in patients treated with other filling implants.

HArmonyCa® contains 0.3% lidocaine hydrochloride, an anesthetic,  

to reduce pain during treatment.

Throughout a 1-year clinical study (N=140), more than 90% of patients saw ongoing visible improvements in their overall facial appearance, which was also validated by investigators.

• 91.8% of patients reported an overall aesthetic improvement at 1 month,  

and 72.6% at 1 year. 

• Investigators reported that approximately 98.5% of patients had an overall aesthetic improvement at 1 month, and 75.6% at 1 year.

A survey of patients treated (N=45) with HArmonyCa® found that most patients  

were highly satisfied with their treatment (mean of 4.1 out of 5) after 19 months.

Powered by DART™, HArmonyCa® is a dual-action injectable designed for patients with facial skin laxity. It offers a comprehensive approach that addresses multiple signs of aging in one treatment.

Signs to help identify yourself as a HArmonyCa® patient: 

• Lack of skin firmness 

• Mild/moderate lateral skin sagginess 

• Accordion lines 

• Mild/moderate jowling 

• Low/moderate volume loss 

During the consultation, patients should be advised about the potential benefits of HArmonyCa®.  

HArmonyCa® can be used only in certain areas of the face, so depending on their specific facial concerns, they should be advised whether it is a suitable treatment for them.

HArmonyCa® is a generally well-tolerated treatment with minimal downtime.

Common postoperative adverse events include erythema, edema, pain, tenderness, itching, lumps or bumps, firmness, bruising, and discoloration.

Treatment site reactions typically resolve within 24–48 hours and swelling within a week.

Patients should be instructed to abstain from use of makeup in the area to be treated for 12 hours before and after the procedure. 

After treatment, the patient should avoid strenuous activity and exposure to sunlight, tanning lamps, or extreme weather conditions for 24 hours in order to reduce redness, swelling, and irritation. They may also apply an ice pack or cold compress. 

If nodules appear, the patient should massage the area. Allow four weeks between ultrasound-based treatments, laser, or peeling treatments and the use of HArmonyCa®.